Cryodepleted plasma

Cryodepleted plasma is plasma that has had some blood clotting proteins (cryoprecipitate) removed. It is mostly used for a condition known as thrombotic thrombocytopenic purpura (TTP).

What is cryodepleted plasma? 

Cryodepleted plasma is the plasma remaining after some blood clotting proteins (cryoprecipitate) have been removed from fresh frozen plasma. It is stored frozen and thawed when required. 


Why might I need to be transfused with cryodepleted plasma? 

You may need a cryodepleted plasma transfusion if you have Thrombotic Thrombocytopenic Purpura (TTP).
TTP is a blood disorder that causes blood clots to form in small blood vessels around your body.
The usual treatment for TTP is plasma exchange where some of your plasma is removed and replaced
with cryodepleted plasma. Occasionally cryodepleted plasma is used to treat other medical conditions.

Are there options other than a cryodepleted plasma transfusion?

There are no other options available to treat TTP that do not involve transfusion of blood products. Sometimes plasma or albumin is used instead of cryodepleted plasma. Both are blood products. Choosing not to receive a transfusion may have severe or fatal consequences.

Learn more about avoiding a transfusion and having a transfusion.